Just five days after tying the knot with partner Karl Cook, the superstar was forced to undergo shoulder surgery.
Cuoco shared the news on Instagram with a quirky snap.
Kaley captioned the photo: "When your ‘honeymoon’ is shoulder surgery and your husband looks just as happy lol on the road to recovery - thank you for all the love and support! knowing @mrtankcook I’m sure he will be posting tons of hilarious gems".
Karl also shared a snap of his new wife in hospital post-surgery.
The newlywed couple didn't disclose just what caused the urgent shoulder surgery though.
Kaley and Karl officially tied the knot on June 30 in an intimate ceremony in San Diego with close friend and family, including Big Bang co-stars Mayim Bialik and Johnny Galecki.
We wish Kaley a speedy recovery!